Stimulation of the nucleus accumbens as behavioral reward in awake behaving monkeys

Narcisse P Bichot, Matthew T Heard, Robert Desimone. Journal of neuroscience methods, Jun 2011.


It has been known that monkeys will repeatedly press a bar for electrical stimulation in several different brain structures. We explored the possibility of using electrical stimulation in one such structure, the nucleus accumbens, as a substitute for liquid reward in animals performing a complex task, namely visual search. The animals had full access to water in the cage at all times on days when stimulation was used to motivate them. Electrical stimulation was delivered bilaterally at mirror…